RPSC SSO 2019 Paper Serology Part A Biochemistry

RPSC Senior Scientific Officer Serology Part A Biochemistry Paper 2019
Total Questions – 100 Duration – Two hours
Part A – Biochemistry – 60 Questions

Formation of Dihydro Oratic Acid takes place during
(a) Biosynthesis of Pyrimidines
(b) Biosynthesis of Purines
(c) Interconversion of Purine Nucleotides
(d) Purine Catabolism

Which one of these is also known as Kornberg Enzyme?
(a) DNA Polymerase-I
(b) DNA Polymerase-II
(c) DNA Polymerase-III
(d) Taq DNA polymerase

Coenzyme used in transamination reaction
(a) NAD
(b) FAD
(c) TPP
(d) PLP

Which out of the following coenzymes takes part in the Hydrogen Transfer Reaction in the Electron Transport Chain?
(a) Tetrhydrofolate
(b) Methyl cobalamine
(c) Ubiquinone
(d) Biotin

Which graphical method is used to determine an enzyme degree of cooperativity?
(a) Hill’s plot
(b) Hanes plot
(c) Michaelis-Menton plot
(d) Lineweaver-Burk plot

Assertion (A) – One drawback from the Eadie-Hofstee approach is that neither ordinate nor Abscissa represents independent variables.
Reason (R) – In Eadie-Hofstee plot, ordinate and Abscissa, both are dependent on reaction velocity.
(a) Both (A) and (R) are individually true and (R) is the correct explanation of (A).
(b) Both (A) and (R) are individually true but (R) is not the correct explanation of (A).
(c) (A) is true but (R) is false
(d) (A) is false but (R) is true.

LDH is found in how many Isoenzyme forms?
(a) 2
(b) 3
(c) 4
(d) 5

The conformational change in the enzyme after the substrate is bound, that allows the chemical reaction to proceed, can be best explained by
(a) Lock and key model
(b) Induced fit model
(c) Allosteric inhibition
(d) Non-competitive inhibition

With four alleles, how many different combinations of alleles can be there?
(a) 4
(b) 8
(c) 12
(d) 16

Holandric gene is
(a) a mutant gene
(b) present on X chromosome only
(c) present on Y chromosome only
(d) present on both X and Y chromosomes